Fast NMR

Abstract

Three major contributions to the field of Fast NMR techniques are presented. They aim at allowing chemists or biologists to probe structural changes occurring in their sample, on a time scale that is adapted to the observation, the description and the understanding of the (bio)chemical processes under study: (i) the SOFAST approach has been developed to acquire experiments on macromolecules with a high acquisition rate, when band-selective excitation schemes are used; (ii) ultrafast NMR allows to record multi-dimensional spectra within a single scan; and (iii) in gradient frequency encoded NMR, the higher resolution of the correlation spectra makes a straightforward assignment and measurement of spin interactions possible, which leads to an acceleration of the whole analytical process.