Cloning and Characterization of a Drosophila melanogaster cDNA Encoding a Glutamate Transporter

Abstract

A Drosophila cDNA encoding a glutamate transporter was cloned and examined. The predicted protein (479 amino acid residues) shows significant sequence identity with mammalian counterparts. The protein expressed in Xenopus oocytes had a glutamate transport activity. Northern blot analysis showed that the transcript increased in amount developmentally. This expression pattern is different from those of Drosophila glutamate receptors. © 1999, Taylor & Francis Group, LLC. All rights reserved.