Construction of spherical virus-inspired peptide nanoassemblies

Abstract

Applications of natural viruses to nanotechnology have attracted much attention due to their fascinating nanostructures. However, chemical strategy to de novo design virus-like nanostructures is still in its infancy. In this review article, we describe novel C 3-symmetric molecular design of peptides and their characteristic self-assembly into virus-like nanostructures. We have developed trigonal conjugates of Β-sheet-forming peptides, trigonal conjugates of glutathione and a viral Β-annulus peptide fragment. © 2012 The Society of Polymer Science, Japan (SPSJ) All rights reserved.