Preimplantation filling of tooth socket with β-tricalcium phosphate/polylactic-polyglycolic acid (β-TCP/PLGA) root analogue: clinical and histological analysis in a patient

Abstract

Introduction. Bone resorption is a physiological process after tooth extraction. The use of bone substitutes to fill the tooth socket is suggested to prevent bone resorption and establish good bone architecture for implant placement. A pure ?-tricalcium phosphate coated with copolymer (polylactic-polyglycolic acid) as a root analogue, is suitable for filling tooth sockets. Case report. We presented a patient successfully treated with root analogue after extraction of the right second lower premolar. Three months later, the patient was planned for the placement of six TE? ITI dental implants into the mandible. During the surgery, the biopsy of bone-like tissue from the previously treated socket was taken. All the implants were immediately loaded due to good primary stability. Histological analysis of the specimen revealed fibrous healing in the area treated with root analogue. Conclusion. The use of ?-tricalcium phosphate coated with copolymers after tooth extraction enables satisfactory bone architecture for consequent implant treatment.Uvod. Resorpcija kosti je fizioloski proces koji nastaje nakon ekstrakcije zuba. Primena kostanih zamenika za popunjavanje alveola nakon ekstrakcije zuba preporucuje se u cilju sprecavanja resorpcije kosti i ocuvanja njene arhitekture pre ugradnje dentalnih implantata. Analog korena zuba, sastavljen od ?-trikalcijum-fosfata oblozenog kopolimerom (polilaktatna poliglikolna kiselina), pogodan je za terapiju ekstrakcione alveole. Prikaz bolesnika. Prikazan je pacijent sa uspesnim popunjavanjem ekstrakcione alveole drugog donjovilicnog premolara sa analogom korena zuba. Tri meseca kasnije kod pacijenta je ugradjeno sest ITI TE? implantata u donju vilicu i tom prilikom izvrsena je biopsija kostanog tkiva predhodno tretirane alveole. Svi implantati odmah su optereceni zbog dobre primarne stabilnosti. Histoloski nalaz bioptickog uzorka ukazao je na fibrozno zarastanje u tretiranoj ekstrakcionoj alevoli. Zakljucak. Upotreba ?-trikalcijum-fosfata oblozenog kopolimerom za popunjavanje ekstrakcione alveole zuba omogucava postizanje zadovoljavajuce arhitekture kosti za buducu terapiju dentalnim implantatima. PR Projekat Ministarstva nauke Republike Srbije, br. 175021