Preliminary studies on the hypoglycaemic effect of abroma augusta in alloxan diabetic rats

Abstract

The hypoglycemic effect of the aqueous extract of Abroma augusta (Family : Steculiceae) was studied in normal as well as alloxan diabetic rats. Treatement of diabetic rats with 4 ml (4gm dry weight) of agueous extract of A. augusta for 16 weeks resulted in gradual but significant fall in fasting blood glucose and improvement in glucose tolerance. Serum total and LDL cholesterol and triacylglycerol which increased in diabetic rats showed improvement/These results show that the water extract of A. augusta has both hypoglycemic and hypocholesterolemic effects.