Research on Biological Properties of Ruthenium (III) Heterocyclic Schiff Base Complexes

Abstract

A set of ruthenium complexes of +3 oxidation state were synthesized with the available ruthenium precursors and the synthesized Schiff base ligands. The complexes are formed by the substitution of the ligand in the octahedral metal precursors. Samples are characterized using analytical as well as spectroscopic techniques. To ascertain pharmacological properties binding study with DNA were carried out. Further, cleavage studies were performed with gel electrophoresis. The in vitro antitumor property was analysed in HeLa tumor cell lines.