Conversional synthesis of heteratisine

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Abstract

The first conversional synthesis of heteratisine has been accomplished in 14 steps and 3.2% overall yield from deltaline, mainly including deoxygenation at C-10, removal of the dioxymethylene moiety, O-demethylation, as well as Baeyer-Villiger oxidation.

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Wang, L., Chen, Q. F., & Wang, F. P. (2012). Conversional synthesis of heteratisine. Natural Product Communications, 7(12), 1583–1586. https://doi.org/10.1177/1934578x1200701210

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