Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model

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Abstract

This study investigated the effects of partially hydrolyzed guar gum (PHGG) on the development of pulmonary arterial hypertension using a SU5416/hypoxia rat model. Our results demonstrated that PHGG treatment suppressed the development of pulmonary hypertension and vascular remodeling with an altered gut microbiota composition.

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Sanada, T. J., Hosomi, K., Park, J., Naito, A., Sakao, S., Tanabe, N., … Suzuki, T. (2023, July 1). Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model. Pulmonary Circulation. John Wiley and Sons Inc. https://doi.org/10.1002/pul2.12266

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