A genome scan for hostility: The national heart, lung, and blood institute family heart study

Abstract

This study investigated genetic linkage for three Cook-Medley hostility subscales plus a total hostility score. Genotyping on 387 autosomal short-tandem-repeat polymorphisms was performed on 508 of the larger white families from randomly selected and high CVD risk groups, composed of 2662 subjects. The number of individuals per family with hostility scores ranged from 2 to 42, with an average of 7.4 inviduals per family. The authors found no significant linkage to hostility or any of its subscales.