Isolation, Characterization and Evaluation of the Antioxidant Potential of Different Extracts and Biomolecules of the Roots of Paullinia pinnata (Sapindaceae)

Abstract

Cardiovascular diseases, which are now among the leading causes of death in the world, are increasingly prompting the search for new antioxidant remedies. It is in this context that the chemical study and evaluation of the antioxidant potential of the different extracts of Paullinia pinnata (Sapindaceae), a plant used in the traditional treatment of cardiovascular diseases was carried out. The assessment of antioxidant potential was carried out by the ABTS free radical scavenging method. Phytochemical study of extracts (ethyl acetate and aqueous) of Paullinia pinnata roots isolated epicatechin, laproanthocyanidin A-2, epicatechin-(2β→O→7, 4β→8)-epicatechin-(4β→8)-epicatechin (cinnamtannin B-1) and O-β-D-glucopyranosyloxy-4-methyl-2(5H)-furanone. These compounds were first isolated from the genus Paullinia pinnata from Côte d'Ivoire. Their structures are elucidated by spectroscopic analyses (NMR and MS) in comparison with data from the literature.