Synthesis, crystal structures and biological activities of palladium(II) complexes of benzimidazole and 2-methylbenzimidazole

Abstract

Five palladium(II) complexes (1–5) with benzimidazole and 2-methylbenzimidazole were prepared and characterized by thermal analysis and, IR and NMR spectroscopy. The crystal structures of two of them, trans-[Pd(benzimidazole)2Br2]·2DMSO (1) and trans-[Pd(2-methylbenzimidazole)2I2] (5) were determined by X-ray crystallography, which describe a square planar coordination environment around the Pd(II) ions. Compound 1 crystallizes as a DMSO solvate. The solid state structures of both complexes are stabilized by hydrogen bonding interactions. The biological evaluation of the complexes showed that they exhibited moderate antimicrobial activities but their antidiabetic properties were momentous with respect to the standard drug.