ISOLATION OF THE ACTIVE COMPOUND FROM THE BARK OF Cinnamomum burmanniiAS A SUNSCREEN

Abstract

Our research aimed to extractCinnamomum burmannii stem barks usingethyl acetate solvent, which further followed by the investigation of for the sunscreen potential of the extract. Crude extract, subfraction, and pure isolate were used to prepare lotion formulations and tested for their sun protection factor (SPF) values. The results showed that lotionsprepared from the crude extract or its subfraction had effecacious sunscreen activity, reaching 38.15 ± 0.51. The pure isolate obtained was elucidated by analyzing the spectral data from1H-Nuclear Magnetic Resonance (1H-NMR),13C-NMR, Mass Spectrometry, and Fourier-TransformInfrared Spectroscopy. The pure isolate wasfound to be 2-Propenoic acid, 3-(2-hydroxyphenyl)-, €-having an SPF value of 33.62 ± 0.62, where its lotion formulation had an SPF value of32.14 ± 0.97. Viscosity and pH properties of the prepared lotion met the criteria from the Indonesian National Standard with spreadability and adhesiveness that are convenient for topical application. Taken altogether, the lotions prepared from ethyl acetate extract of C. burmannii could potentially be used as sunscreen agents.