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The Bax pore in liposomes, Biophysics

Cell Death and Differentiation
DOI: 10.1038/sj.cdd.4401991
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Abstract

The protein BAX of the Bcl-2-family is felt to be one of the two Bcl-2-family proteins that directly participate in the mitochondrial cytochrome c-translocating pore. We have studied the kinetics, stoichiometry and size of the pore formed by BAX in planar lipid bilayers and synthetic liposomes. Our data indicate that a cytochrome c-competent pore can be formed by in-membrane association of BAX monomers. © 2006 Nature Publishing Group. All rights reserved.

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Schlesinger, P. H., & Saito, M. (2006, August). The Bax pore in liposomes, Biophysics. Cell Death and Differentiation. https://doi.org/10.1038/sj.cdd.4401991

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