Parametric approach to measuring cerebral blood flow autoregulation from spontaneous variations in blood pressure

Abstract

A parametric linear model fitted to cerebral blood flow velocity (CBFV) and arterial blood flow (ABF) was proposed as a basis for measuring autoregulatory activity. To evaluate the ability of the method to detect altered states of cerebral blood flow control, 60 patients were examined prior to carotid artery endarterectomy. In general, the method allowed simple parametrization of the dynamic autoregulatory responses in CBFV as well as the analysis of short data segments.