Cytotoxic activity of Galantamine hydrobromide against HeLa cell line

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Abstract

Cytotoxic activity of Galantamine HBr against human cervical adenocarcinoma cell line HeLa in different concentrations (1.875 μМ ÷ 30 μМ) was evaluated. Inhibition of HeLa cell growth after treatment with Galantamine HBr and index of cell viability were determined. From the experimental results was proven that the drug exerts cytotoxic activity towards HeLa cell line, with antiproliferative activity presented as the value of IC50 = 30 μM ± 0.22.

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Obreshkova, D., Atanasov, P., Chaneva, M., Ivanova, S., Balkanski, S., & Peikova, L. (2023). Cytotoxic activity of Galantamine hydrobromide against HeLa cell line. Pharmacia, 70(3), 619–623. https://doi.org/10.3897/pharmacia.70.e109841

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