Absence of mutagenic activity in Salmonella typhimurium of some impurities found in saccharin

Abstract

o-Sulphobenzoic acid, o-toluenesulphonamide and ammonium o-sulphobenzoate were assayed for their possible mutagenicity in several Salmonella typhimurium strains. No mutagenic activity was detected towards any strain, at any of the levels tested, either in the absence or presence of fortified rat liver post-mitochondrial fractions. © 1979.