Asymmetrical aerosol deposition in an idealized mouth with a DPI mouthpiece inlet

Abstract

Monodisperse aerosol deposition in an idealized mouth geometry with a dry powder inhaler (DPI) mouthpiece inlet is studied numerically using a standard Large Eddy Simulation (LES). A steady inhalation flow rate of Q = 90 L/min is used. Ten thousand of particles (4.1 μm diameter and 953.0 kg/m3 density) are released individually in the computational domain and aerosol deposition is determined. Total aerosol deposition results for the present idealized mouth are in good agreement when compared with measured data obtained in separate experiments, showing improvement over the standard Reynolds Averaged Navier-Stokes/Eddy Interaction Model (RANS/EIM) approach (without near-wall corrections). Copyright © American Association for Aerosol Research.