New insights into breast and endometrial cancers

Abstract

Cancers of the breast and endometrium are some of the most common cancers affecting women. These cancers show estrogen-dependent proliferation in several cases; therefore, hormone therapeutic strategies are employed. Tamoxifen is an effective hormone therapy that is traditionally used for estrogen receptor-positive breast cancer patients. However, in endometrial cancer, tamoxifen treatment increases the risk of a poor prognosis type of endometrial cancer.