Genetics in epilepsy, Dravet and SUDEP: A systematic review

Abstract

Introduction: Epilepsy is a neurologic condition and its patients have higher mortality rates than healthy individuals. One of the most frequent death causes in epilepsy is SUDEP. Moreover, another cause in epilepsy, although rare, is Dravet Syndrome and it's generally diagnosed in children in their first year of life. In around 70% of the patients there is a genetic inheritance involved and several genes have been described as related to SUDEP and Dravet Syndrome which the most prevalent were DNA and belonged to the voltage-gated channel coding.