Development of a new mobile HMS with glucose sensor in disposable vacuum blood extraction system for blood sugar level measurement

Abstract

In this study, a mobile Health Monitoring System (HMS) for the diabetes patient is newly developed. Main subjects of this HMS design are (1) a painless microneedle with inner diameter less than 100 μm, (2) the vacuum blood extraction of 1 μl, and (3) measurement of blood sugar level by using MOS-FET and Glucose sensor. The vacuum blood extraction system with a microneedle and blood sugar sensor is set in a disposable disc cartridge. Simultaneously, the mechanism of vacuum blood extraction was analyzed, the blood flow rate was measured, and the performance of blood sugar sensor was evaluated. Finally, this HMS succeeded in extracting 3 μl of human blood within 0.3 sec and measuring the blood sugar level by the automatic operation.