Abstract
Lassa virus (LASV) is the causative agent of Lassa hemorrhagic fever (LF) in humans, a deadly disease endemic to West Africa that results in 5,000 to 10,000 deaths annually. Here we present results demonstrating that functional type I and type II interferon (IFN) signaling is required for efficient control of LASV dissemination and clearance.
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APA
Yun, N. E., Poussard, A. L., Seregin, A. V., Walker, A. G., Smith, J. K., Aronson, J. F., … Paessler, S. (2012). Functional Interferon System Is Required for Clearance of Lassa Virus. Journal of Virology, 86(6), 3389–3392. https://doi.org/10.1128/jvi.06284-11
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