Stereoselective manipulation of acetals derived from o-substituted benzaldehyde chromium tricarbonyl complexes

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Abstract

The stereoselective syntheses of mixed acetals derived from o-substituted benzaldehyde chromium tricarbonyl compounds are described. These acetals are shown to undergo highly selective displacement reactions in a process which involves neighbouring group participation from the chromium tricarbonyl unit. Asymmetric syntheses of a-methyl benzylamines and 2-aryl tetrahydropyrans, via this methodology, are described. © 1992 IUPAC

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Davies, S. G., Donohoe, T. J., & Williams, J. M. J. (1992). Stereoselective manipulation of acetals derived from o-substituted benzaldehyde chromium tricarbonyl complexes. Pure and Applied Chemistry, 64(3), 379–386. https://doi.org/10.1351/pac199264030379

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