Abstract
With the advance of sequencing technologies, the landscape of genomic analysis has been transformed, by moving from single strain to species (or even higher taxa)-wide genomic resolution, toward the direction of capturing the "totality" of life diversity; from this scientific advance and curiosity, the concept of "pangenome" was born. Herein we will review, from practical and technical implementation, existing projects of pangenome analysis, with the aim of providing the reader with a snapshot of useful tools should they need to embark on such a pangenomic journey.
Author supplied keywords
- Bayesian
- Binomial mixture model
- Clustering
- Combinatorial approach
- Command line
- Exhaustive search
- Finite supragenome model
- Gene presence/absence frequency
- Hidden Markov Models
- Infinitely many genes model
- ORF alignment similarity
- Ortholog clusters
- Pangenome
- Reference pangenome
- Regression function
- Subsampling
- Web-interface
- Whole-genome
Cite
CITATION STYLE
Vernikos, G. S. (2020). A review of pangenome tools and recent studies. In The Pangenome: Diversity, Dynamics and Evolution of Genomes (pp. 89–112). Springer International Publishing. https://doi.org/10.1007/978-3-030-38281-0_4
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
