Eigen-R2 for dissecting variation in high-dimensional studies

Abstract

We provide a new statistical algorithm and software package called 'eigen-R2' for dissecting the variation of a high-dimensional biological dataset with respect to other measured variables of interest. We apply eigen-R2 to two real-life examples and compare it with simply averaging R2 over many features. © The Author 2008. Published by Oxford University Press. All rights reserved.