Electrophysiological Assessment of the Impact of Mobile Phone Radiation on Cognition in Persons with Epilepsy

Abstract

Purpose: Serious concerns about the effect of mobile phone radiation on cognition are growing. This study aimed to assess the possible effect of mobile phone radiation in persons with epilepsy and in normal subjects. Methods: The amplitude and reaction time of auditory event–related potentials (P300) and occipital alpha frequency were compared before and after exposure with a 30-minute call in 30 persons with epilepsy and in 30 control subjects. Alpha power was monitored before, during, and after exposure to mobile phone radiation. Moreover, correlations with clinical aspects were analyzed. Results: Increased reaction time and decreased P300 amplitude were more evident in persons with epilepsy. A significant decrease in alpha power was noted in control subjects and persons with epilepsy and was associated with an increased bilateral alpha frequency. In persons with epilepsy, such changes significantly correlated with the time since the last seizure and with the therapy regimen. Conclusions: Thirty-minute exposure to mobile phone radiation has a significant effect on the electrophysiological correlates of cognition, especially in persons with epilepsy.