Radioactive‐induced tumors by phosphorus‐32 as colloidal compound

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Abstract

Chromic colloidal phosphate labeled with 32P, which has been proposed for the treatment of several articular diseases, was injected intra‐articularly in the knee joint of adult Wistar rats. After a 270 days minimum latent period, tumors began to appear in the injected zone, to a 70% frequency. Ten lung metastases were detected. In five cases, squamous cell carcinomas were induced in the injected area. The relevance of a sound evaluation of the risk involved in treatments with radioactive isotopes, is discussed. Copyright © 1983 American Cancer Society

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Ubios, A. M., Silberman, F. S., & Cabrini, R. L. (1983). Radioactive‐induced tumors by phosphorus‐32 as colloidal compound. Cancer, 51(9), 1605–1609. https://doi.org/10.1002/1097-0142(19830501)51:9<1605::AID-CNCR2820510909>3.0.CO;2-2

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