Mixed systemic amyloidosis in a patient receiving long term haemodialysis

Abstract

A 64 year old woman had been receiving haemodialysis for 11 years. She had a history of chronic renal failure, caused by probable chronic pyelonephritis, and dialysis arthropathy. She died of acute pulmonary oedema and haemorrhage. At necropsy, histological, immunohistochemical, and ultrastructural studies showed widespread visceral deposits of β2-microglobulin (β2-M) and AA amyloid.