Malignant brenner tumor of ovary

Abstract

Introduction: Ovarian carcinoma remains the most lethal disease of the female reproductive tract and most difficult to diagnose early. Brenner tumor of ovary is a relatively uncommon neoplasm constituting 1.4 to 2.5% of all ovarian tumors. In vast majority of cases, these tumor are benign, only 2.5% being malignant. Case report: A 46 years old parous menopausal female presented with complains of pain in abdomen since 2 months and lump in right iliac region. Per abdomen examination showed irregular mass of variable consistency with 16 to 18 weeks gravid uterus size arising from pelvis. On per vaginum examination, firm to hard mass was felt in the posterior and lateral fornices exact size of which could not be determined. Per rectal examination revealed hard nodules in Pouch of Douglas (POD). Ovarian cytoreduction surgery was performed. Omentectomy was performed. Histopathology showed malignant Brenner tumor (transitional cell carcinoma). Conclusion: Although Brenner tumors are rare and the majority of them are benign, the correct histological diagnosis with identification of the small proportion of malignant tumors allows the extent of the operation to be needed.