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Take my breath away: TAM-ing anti-cancer immunity in hypoxic niches

Immunity
DOI: 10.1016/j.immuni.2023.07.010
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Abstract

Hypoxia is a major driver of tumor aggressiveness and therapy resistance in GBM. In this issue of Immunity, Sattiraju et al. functionally link hypoxia with diminished anti-cancer immunity caused by sequestration of immunosuppressive TAMs and CTLs in pseudopalisades in GBM.

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Möckl, A., & Sevenich, L. (2023, August 8). Take my breath away: TAM-ing anti-cancer immunity in hypoxic niches. Immunity. Cell Press. https://doi.org/10.1016/j.immuni.2023.07.010

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