Antibacterial activity of three macrofungi, Ganoderma lucidum, Navesporus floccosa and Phellinus rimosus occurring in South India

Abstract

Antibacterial activity of the methanol extract of three polypore macrofungi Phellinus rimosus, Ganoderma lucidum and Navesporus floccosa were studied. The activity was evaluated by hole-plate diffusion and microtitre plate dilution methods using Escherichia coli, Pseudomonas aeuroginosa, Staphylococcus aureus, Salmonella typhimurium, and Bacillus subtilis. The methanol extract of P. rimosus and N. floccosa showed activity against all the strains at a concentration of 800 μg/well and 1 mg/well, respectively. The methanol extract of G. lucidum showed activity against E. coli, S. typhimurium and B. subtilis at a concentration of 1 mg/well. The minimum inhibitory concentration (MIC) of P. rimosus and N. flocossa were found to be 500 μg/well and 1 mg/well, respectively. The MIC of G. lucidum was also found to be 1 mg/well. Chemical analysis of the methanol extracts of these fungi indicated the presence of polyphenols, flavonoids, quinones and terpenes.