Clinical Scales in Aneurysm Rupture Prediction

Abstract

The rate of incidentally discovered unruptured intracranial aneurysms has increased with the broad availability of neuroimaging. The determination of the risk of rupture of brain aneurysms is challenging. Several clinical scales for aneurysm rupture prediction have been developed. The most common scales are PHASES, ELAPSS, and UIATS. These scales are not routinely used in clinical practice due to inherent shortcomings. In this review, we analyze the risk factors used in generating these scales and the performance of these scales in clinical studies. We also discuss new potential biomarkers and tools to predict aneurysm rupture.