Allelic diversity of the Helicobacter priori vacuolating cytotoxin gene in South Africa: Rarity of the vacA s1a genotype and natural occurrence of an s2/m1 allele

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Abstract

We describe the rarity of Helicobacter pylori strains of vacuolating cytotoxin type s1a (the type most commonly associated with peptic ulceration in the United States) among black and mixed-race South Africans. We also provide the first description of a naturally occurring strain with the vacA allelic structure s2/m1.

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Letley, D. P., Lastovica, A., Louw, J. A., Hawkey, C. J., & Atherton, J. C. (1999). Allelic diversity of the Helicobacter priori vacuolating cytotoxin gene in South Africa: Rarity of the vacA s1a genotype and natural occurrence of an s2/m1 allele. Journal of Clinical Microbiology, 37(4), 1203–1205. https://doi.org/10.1128/jcm.37.4.1203-1205.1999

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