Extracorporeal cytokine removal in chimeric antigen receptor T-cell therapy associated cytokine release syndrome in patient with acute lymphoblastic leukemia. Case report

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Abstract

Сytokine release syndrome is the common complication of CAR-T therapy. We report a case of patient with B-cell acute lymphoblastic leukemia developing сytokine release syndrome with shock and multiple organ failure and requiring cytokine removal and hemodiafiltration. Remission of the disease was achieved after CAR-T therapy.

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Shchekina, A. E., Galstyan, G. M., Gavrilina, O. A., Arapova, N. M., Bronyakina, S. Y., Kotova, E. S., … Savchenko, V. G. (2021). Extracorporeal cytokine removal in chimeric antigen receptor T-cell therapy associated cytokine release syndrome in patient with acute lymphoblastic leukemia. Case report. Terapevticheskii Arkhiv, 93(7), 811–817. https://doi.org/10.26442/00403660.2021.07.200931

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