A new anthelmintic cyclodepsipeptide, pf1022a

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Abstract

The novel anthelmintic cyclodepsipeptide PF1022A was isolated from cultured mycelia of Mycelia Sterilia PF1022 (FERM BP-2671). It showed strong anthelmintic activities against Ascaridia galli in chickens. The structure of PF1022A was determined to be cyclo(D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-methylleucyl-D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-methylleucyl) by spectroscopic analyses and chemical studies. © 1992, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

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Sasaki, T., Takagi, M., Yaguchi, T., Miyadoh, S., Okada, T., & Koyama, M. (1992). A new anthelmintic cyclodepsipeptide, pf1022a. The Journal of Antibiotics, 45(5), 692–697. https://doi.org/10.7164/antibiotics.45.692

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