The aqueous extract of the aerial parts of Lippia integrifolia has been assayed for its choleretic and antispasmodic effects. Doses of 250, 500 and 750 mg/kg administered orally in rats significantly increased the bile flow and the bile acid output. The extract also showed a significant reduction of the contractions induced by acetylcholine, CaCl2 and KCl on isolated rat jejunum. The total caffeoyl quinic acids derivatives content, expressed as chlorogenic acid was 0.10% w/v by spectrophotometric determination.
CITATION STYLE
Gorzalczany, S., Sülsen, V., Redko, F., Vescina, C., Muschietti, L., Martino, V., & Acevedo, C. (2008). Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract. Revista Brasileira de Farmacognosia, 18(1), 16–20. https://doi.org/10.1590/S0102-695X2008000100005
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