Simple reduction of ethyl, isopropyl and benzyl aromatic esters to alcohols using sodium borohydride-methanol system

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Abstract

Several aromatic ethyl, isopropyl and benzyl esters were reduced to their corresponding alcohols in sodium borohydride-methanol system. The reductions were completed within 15-60 minutes in refluxing THF. The alcohol products were isolated after aqueous workup in good to excellent yields (63-100%). The general procedure presented is simple, safe, inexpensive and with good perspective in industrial scale. ©ARKAT.

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Da Costa, J. C. S., Pais, K. C., Fernandes, E. L., De Oliveira, P. S. M., Mendonça, J. S., De Souza, M. V. N., … Vasconcelos, T. R. A. (2006). Simple reduction of ethyl, isopropyl and benzyl aromatic esters to alcohols using sodium borohydride-methanol system. Arkivoc, 2006(1), 128–133. https://doi.org/10.3998/ark.5550190.0007.115

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