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Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions

Genome Biology (2015) 16(1)
DOI: 10.1186/s13059-015-0778-y
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Abstract

Cell-cycle fluctuations drive significant transcriptomic heterogeneity in murine hematopoietic stem cells. Additionally, deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice.

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Powers, A. N., & Satija, R. (2015). Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions. Genome Biology, 16(1). https://doi.org/10.1186/s13059-015-0778-y

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