Chiral palladium complex-catalyzed synthesis of optically active vinylchroman

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Abstract

Optically active vinylchroman (1) was synthesized from a corresponding allyl carbonate (2) by catalytic and asymmetric allylic substitution with palladium complexes of chiral bisphosphine ligands. The reactivity and selectivity of the various chiral bisphosphine-palladium complexes were investigated.

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Mizuguchi, E., & Achiwa, K. (1997). Chiral palladium complex-catalyzed synthesis of optically active vinylchroman. Chemical and Pharmaceutical Bulletin, 45(7), 1209–1211. https://doi.org/10.1248/cpb.45.1209

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