Value of the eazyplex® csf direct assay in rapid diagnosis of invasive meningococcal disease -Case report

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Abstract

There is a need for easy-to-use molecular assays for diagnosis of invasive meningococcal disease. Here, we report the rapid identification of Neisseria meningitidis in a cerebrospinal fluid sample from a patient with purulent meningitis using a commercially available loop-mediated isothermal amplification assay, resulting in a prompt de-escalation of the initial empiric antibiotic therapy.

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Karrasch, M., Eisenach, S., Vogel, U., Zinke, J., Witte, O. W., Günther, A., … Rödel, J. (2018). Value of the eazyplex® csf direct assay in rapid diagnosis of invasive meningococcal disease -Case report. Acta Microbiologica et Immunologica Hungarica, 65(3), 309–315. https://doi.org/10.1556/030.65.2018.021

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