The solvent free preparation of β-amino esters α,β- unsaturated ketones and esters with domestic microwave oven

Abstract

A series of β-amino esters α,β-unsaturated ketones and esters 4a-h and 6a-d derived from α-amino acids have been prepared starting from a-amino esters hydrochorides 2a-d with 1,3-dicarbonyl compounds 3a,b and 5 in presence of triethylamine. These compounds have been prepared under domestic microwave oven, under solvent free condition with and without solid support (K-10 or KSF). © 2006 Sociedade Brasileiva de Química.