Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer’s disease

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Abstract

Our understanding of Alzheimer’s disease (AD) has evolved from focusing solely on neurons to recognizing the role of glia. A recent study in PLOS Biology revealed that oligodendrocytes are an important source of Aβ that impairs neuronal function.

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Spieth, L., & Simons, M. (2024). Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer’s disease. PLoS Biology, 22(9 September). https://doi.org/10.1371/journal.pbio.3002798

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