Clinical Characteristics of Tuberculosis Among People Living with Human Immunodeficiency Virus (HIV): A Multicenter Study

Abstract

Objective: The intersection of human immunodeficiency virus (HIV) and tuberculosis (TB) presents a significant public health challenge, particularly in regions with high prevalence of both diseases. This multicenter, retrospective study aimed to evaluate the clinical characteristics, treatment outcomes, and factors influencing the development of TB in individuals infected with HIV. Materials and Methods: This multicenter, retrospective study included individuals infected with HIV from 15 centers, assessing demographic and disease-related data. Inclusion criteria encompassed HIV patients over 18 years of age with TB treatment histories. Data analysis utilized SPSS Statistics version 25.0, adhering to the ethical principles of the Declaration of Helsinki. Results: The study included 9,720 HIV-infected patients from 15 centers, with TB detected in 124 (1.28\%) of these individuals. The majority were male, and the median age at TB diagnosis was 43 years. Clinical findings revealed that pul