Behaviour of some activated nitriles toward barbituric acid, thiobarbituric acid and 3-methyl-1-phenylpyrazol-5-one

Abstract

The effect of some active methylene containing heterocyclic compounds, namely barbituric acid, thiobarbituric acid and 3-methyl-1-phenylpyrazol-5-one on α-cyano-3,4,5-trimethoxycinnamonitrile and ethyl α-cyano-3,4,5- trimethoxycinnamate (1a,b) was investigated. The structure of the new products was substantiated by their IR, 1H-NMR and mass spectra.