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Cladospolide D, a new 12-membered macrolide antibiotic produced by Cladosporium sp. FT-0012

Journal of Antibiotics (2001) 54(8) 635-641
DOI: 10.7164/antibiotics.54.635
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Abstract

A new antibiotic termed cladospolide D was isolated along with the known cladospolides A and B from the fermentation broth of Cladosporium sp. FT-0012 by solvent extraction, ODS column chromatography and preparative HPLC. The structure of cladospolide D was deduced to be (E)-2-dodecen-5-hydroxy-11-olide-4-one. Cladospolide D showed antifungal activity against Pyricularia oryzae and Mucor racemosus.

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Zhang, H., Tomoda, H., Tabata, N., Miura, H., Namikoshi, M., Yamaguchi, Y., … Omura, S. (2001). Cladospolide D, a new 12-membered macrolide antibiotic produced by Cladosporium sp. FT-0012. Journal of Antibiotics, 54(8), 635–641. https://doi.org/10.7164/antibiotics.54.635

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