Facing up to Mena: Tes(ting) times for EVH1 domains

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Abstract

Ena/VASP family members have a common binding interface on their EVH1 domains for FPPPP motifs in partner proteins. The finding that Tes, a protein lacking FPPPP motifs, competes specifically for the FPPPP ligand site on Mena, provides new insights into the differential regulation of Ena/VASP proteins.

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Small, J. V. (2008). Facing up to Mena: Tes(ting) times for EVH1 domains. Nature Cell Biology, 10(2), 118–120. https://doi.org/10.1038/ncb0208-118

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