The first enantioselective and diastereoselective catalytic nitro-Mannich reaction: A new entry to chiral vicinal diamines

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Abstract

The first example of an enantioselective and diastereoselective catalytic nitro-Mannich reaction using a second-generation heterobimetallic complex has been developed. The corresponding nitro-Mannich products were obtained in up to 83% ee with a dr up to 7:1.

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Yamada, K. I., Moll, G., & Shibasaki, M. (2001). The first enantioselective and diastereoselective catalytic nitro-Mannich reaction: A new entry to chiral vicinal diamines. Synlett, (SPEC. ISS), 980–982. https://doi.org/10.1055/s-2001-14639

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