The effect of autologous platelet rich plasma in the treatment of achilles tendon ruptures: An experimental study on rabbits

Abstract

Objectives: The aim of this study was to determine the effect of autologous platelet rich plasma (PRP) in the treatment of Achilles tendon ruptures in rabbits. Methods: The study included 14 New Zealand albino rabbits that were divided randomly into 2 groups, A and B, each containing seven rabbits. On day zero, all 28 Achilles tendons were tenotomized and repaired. In group A, the tendons were injected with PRP post surgery whereas those in group B were left untreated. On day 28, the right tendons in both groups were examined histopathologically via both light and electron microscopy, and the left tendons were subjected to biomechanical testing. Results: The histological and biomechanical findings in group A were better than those in group B, but the difference was not significant. Conclusion: PRP had no effect on the healing process 28 days post Achilles tendon rupture.