Membrane surface orientation and motion of glycolipids: 2H NMR investigations

Abstract

By means of measured quadrupole splittings, dipole-dipole couplings, and lineshape analysis, the degree of motional restriction (ordering) and bilayer orientation of glvcolipid head groups can be calculated. From the dependence of the 2H nmr lineshape on multipulse experiments, and from a variety of relaxation time measurements, insight into the rates of motion (103-1011s-1) of the carbohydrate species can be gained. Various slow motions (< 103 s-1) may be visualized by means of a solid state two-dimensional 2H nmr technique. © 1991 IUPAC