Spectroscopic studies of methimazole reactivity toward the aquapentacyanoferrate (II) ion in aqueous solutions

Abstract

Methimazole (2-mercapto-1-methylimidazole, MMI) and its pentacyanoferrate (II) complex have been characterized by means of UV/Vis, Raman, and NMR spectroscopy. The reaction of MMI with aquapentacyanoferrate (II), [Fe(CN)H)]3-, in buffered aqueous solutions yielded the [Fe(CN)MMI)]3- complex. It was found that only thione tautomer of MMI coordinates to the iron (II). The exceptionally stabile and inert complex was produced. © 2012 D. Cvijanović et al.