Potential triggers of lichen planus: A review

Abstract

Oral lichen planus (OLP) is mucocutaneous and chronic inflammatory disease of unclear pathogenesis. OLP usually affects the mucous membrane of oral cavity. It is an autoimmune disorder araising from several etiological factors like genetics, stress, virus, dental restorative materials, drugs and systemic diseases. It is a T-cell mediated autoimmune disease usually encountered by dentists and dermatologists. Although much work is being done on this disorder, there is still uncertainty over the specific etiopathogenesis and treatment. Because there is a risk of reported malignant potential with this disease, the patient needs early diagnosis and proper management. This article reviews mainly the etiology, pathogenetic mechanisms through which this unique disorder occurs along with the aspects of clinical, histopathological and treatment.